Aim:

To assess the compare the efficacy of Fosfomycin vs Nitrofurantoin in the treatment of urinary tract infection in tertiary care hospital.

Material and Methods:

A total of 120 urine sample were collected from patients presenting with UTI. Mueller Hinton Agar was used in the disc diffusion technique to test for antibiotic resistance. Fosfomycin (300 ug) and Nitrofurantoin (300 ug) discs were used.

Results:

The mean age of the patients were 45.94±9.49 years. The most prevalent uropathogen found were E.coli and Klebsiella. Sensitivity of isolated Uropathogens against Fosfomycin and Nitrofurantoin was 96.7% and 80%.

Conclusion:

Fosfomycin showed better efficacy as compared to Nitrofurantoin against uropathogens.

Keywords: Urinary Tract Infection, Fosfomycin, Nitrofurantoin.