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PREVALENCE AND RISK FACTORS RELATED TO POLYCYSTIC OVARIAN SYNDROME FEMALES WITH REPRODUCTIVE AGE

. Maryam Ali Malik, Sadia Iftikhar, Asim Raza, Farooq Islam and Muhammad Yahya Shafiq


Abstract

Background: Polycystic Ovarian syndrome (PCOS) is one of the frequent endocrine diseases in reproductive-age women. Objective of this current study was to estimate the prevalence and risk factors related to polycystic ovary syndrome (PCOS) among women of reproductive age.

Methods: An analytical cross-sectional study was carried out on 385 females of reproductive age 15-44 years that were selected with non-probability convenient sampling during May to August 2022 from general population of Gujrat. Selection of participants was done on the basis of the inclusion and exclusion criteria. NIH (1990) criteria were used as a diagnostic tool for the conformation of PCOS and hirsutism was observed by Modified Ferriman-Gallwey scale. Statistical Package for the Social Sciences (SPSS) version 24.0 was used to analyze the data at 95% confidence interval. Chi Square test applied to find the association of PCOS with factors. 

Results: Out of 385 females of age 15 to 44 years, average age 28.95±7.90 years, BMI 28.46±5.00 kg/m2 and age of menarche 12.80±1.40 years was observed. Out of total, 101 (26%) were diagnosed with PCOS. Menstrual interval longer than 35 days, abnormal menstruation, acne, family history of infertility, depression/ anxiety, lack of physical exercise and patient history of hypertension was found statistical significant with p-value <0.005 between  PCOS and without PCOS

Conclusion: Prevalence of PCOS was observed fourth part of study population. Potential risk factors of PCOS females were observed menstrual cycle disorder, family history of infertility, depression, Acne and lack of physical exercise of female population. Hirsutism, acne, dysmenorrhea and oligomenorrhea were most common phenotype observed in PCOS. On the basis of findings concluded that more than half females of reproductive age were conformed to PCOS

Keywords: Body mass index, hirsutism, polycystic ovarian syndrome (PCOS), national Institutes of health criteria (NIH), risk factors.

 

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