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EVALUATION OF VITAMIN D SUPPLEMENTATION ON PERIODONTITIS AND OSTEOCALCIN LEVEL AFTER NON-SURGICAL PERIODONTAL THERAPY

. Raffat un Nisa,Ayesha Imtiaz, Madiha Farooqui, Ambreen Khurshid Haider, Alamgir and Saba Abrar


Abstract

Background:

Vitamin D has anti-inflammatory properties as well as the potential to increase antimicrobial production. A higher intake of vitamin D has also been linked to a lower risk of periodontal disease progression and an increase in Osteocalcin bone mineralization.

Aim:

The primary goal of this study was to evaluate and compare periodontitis clinical parameters before and after oral vitamin D supplementation as adjuvant to Non-surgical Periodontal Treatment as well as to evaluate salivary Osteocalcin bone mineralization levels in chronic periodontitis patients.

Methodology:

This study included 50 patients with periodontitis divided into two groups of 25 patients in each group, Group I receiving only nonsurgical periodontal therapy and Group II receiving both nonsurgical periodontal therapy and vitamin D supplementation. Clinical parameters included plaque index, gingival index, probing pocket depth, clinical attachment loss and Osteocalcin level. Serum vitamin D levels were measured at baseline and 6 weeks after Nonsurgical Periodontal Therapy.

Results:

At 6 weeks, the inter-group comparative of clinical parameters (PI, GI, PPD, and CAL) for both groups revealed statistical significance. In both groups, an intra-group comparative of clinical parameters from baseline to 6 weeks revealed a statistically significant reduction. The Osteocalcin level in the test group increased significantly following vitamin D supplementation as an adjuvant to nonsurgical periodontal treatment.

Conclusion:

A highly significant reduction in periodontitis was observed in the vitamin D supplementation group, indicating a positive relationship between vitamin D supplementation adjuvant to NSPT and improving periodontal symptoms.

Keywords: Vitamin D, Periodontitis, Osteocalcin, Non-Surgical Periodontal Treatment, Plaque Index, Gingival Index, Periodontal Probing Depth, Clinical Attachment loss.

 

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