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FREQUENCY OF NEUROLOGICAL OUTCOME IN ECLAMPTIC PATIENTS VISITING CIVIL HOSPITAL KARACHI

. Asma Safdar Syed and Zakia Bano


Abstract

Objective:Pregnancy-induced hypertension (PIH), a leading cause of maternal morbidity and death, may be a significant predictor of pregnancy-associated intra-cerebral hemorrhage (ICH). Therefore, this study was planned to determining the neurological outcomes associated with eclamptic women during pregnancy.

Methodology:This was a cross-sectional study, which was conducted in the Department of Obstetrics and Gynecology at Civil Hospital Karachi, using non-probability sampling technique. The study duration was about six months, from October 2021 to March 2022. The study included 94 patients aged 16 to 40 years who were diagnosed with eclampsia during a pregnancy of more than 20 weeks, whether booked or not, and of any parity. Parity and maternal age were presented as Mean and Standard Deviation. For the presentation of qualitative variables including prenatal booking status, signs and symptoms, and intra cerebral hemorrhage, frequencies and percentages were computed.

Results:The study results showed that out of 94 patients,37 (39.4%), were between the ages of 16 and 20; 23 (24.5%) were between the ages of 21 and 25; 24 (25.5%) were between the ages of 26 and 30. Most of the patients 70 (74.5%) were unscheduled to have none orno more than three antenatal visits. Parity status revealed that 47 (50.0%) patients were nulliparous. Headache was the most common signs or symptoms of intra-cerebral hemorrhage in 39(41.5%)women, followed by seizures 23(24.5%). Intra-cerebral hemorrhage was observed in only 2 (2.9%) patients in un-booked antenatal cases. While most of the patients 68 (99.1%) did not report intra-cerebral hemorrhage.

Conclusion: This study concluded that neurological symptoms such as seizures and headache were more common in patients with eclampsia. Un-booked cases accounted for the majority of intra cerebral hemorrhages.Only a few patients reported maternal death as a result of intra-cerebral hemorrhage, which was most common in nulliparous and multigravida women.

Keywords: Intra-cerebral hemorrhage, eclampsia, pregnancy, seizures, headache

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