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Applied study of Dhatwagni Siddhanta by Comparative evaluation of Kiratatiktadi Ghanavati versus Tryushnadi Guggulu in management of Medodushtijanya Vikara (in context of Dyslipidemia)

. Maltee Patel, Dnyanesh Joshi, Preeti Borkar & Bhushan Mhaiskar


Abstract

Background: Dyslipidemia is a lifestyle disorder that is frequently seen. It affects people of all ages and sexes equally. A condition known as dyslipidemia is characterised by abnormally high the level of total Cholesterol, VLDL, LDL, triglycerides and HDL in blood and this disorder is brought on by an abnormal lipid and lipoprotein metabolism and carries the risk of producing a number of complications, including cardiovascular disease, diabetes, obesity, hypertension, and others. The pathophysiology and clinical manifestation of dyslipidemia and medodushtijanya vikara are very similar. kiratatiktadi ghanavati will be work for the medodushtijanya vikar. As the outcome of this study will be positive i.e, the drug has vital action in mananagement for the Dyslipidemia. Aim : Revalidation the concept of Dhatwagni Siddhant by a comparative clinical evaluation of Kirattiktadi Ghanavati with Tryushnadi Guggulu in Medodushtijanya Vikara (in context of Dyslipidemia). Objectives: To explore the concept of Dhatwagni, and to explain the Medodushtijanya Vikara in context to Dhatwagni. To evaluate the efficacy of Kiratatiktadi Ghanvati in the Medodushtijanya Vikara through the correction of Dhatwagni. To compare the efficacy of Kiratatiktadi Ghanavati and Tryushnadi Guggulu in the Medodushtijanya Vikara through the correction of Dhatwagni. Methodology: It is double arm randomized standard control single blind superiority clinical study. A total of 60 patients will be randomized into two groups at random (Every group contain 30). In Group A, Tryushnadi Guggulu 2 vati (500 mg of each) once a day, before meal with koshna jala will be given for 30 days and Group B will be given Kirattiktadi Ghanavati 2 vati (500 mg of each) once a day, before meal with koshna jala will be given for 30 days. Assesment will be done on 15th and 30th day. Results: Result will be declear on the basis of effect of Kirattiktadi Ghanavati with lipid profile test. Conclusion: This trial may provide evidence on the efficacy of Kirattiktadi Ghanavati in Dyslipidemia.

Keywords: Dyslipidemia, medodushti janya vikara, Kirattiktadi Ghanavati, Tryushnadi Guggulu, lipid profile test.

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