Objective/Background: To calculate the survival and mortality rates among patients with COVID-19 pandemic.

Methodology: A single central retrospective cross-sectional study was conducted on 993 patients of COVID-19 from Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan.   Retrospective data was collected using patients reports of duration March, 2020 to January, 2022  from admitted patients of COVID-19 that were isolated in tertiary care hospital. All data was entered and analyzed in SPSS (Version 24.00). P-value ≤0.05 was considered as significant value.

Results: Total patients (993) of COVID-19 with average age 44.30±20.24 years from which 547 (55.09%) were male. Out of 993 COVID-19 patients, 507 (51.10%), 243 (24.50%), 193(19.40%), 30(3.00%) and 20 (2.00%) were selected from 1st, 2^nd ,3^rd, 4^th and 5^th waves of pandemic COVID-19  from which mortalities were observed 394 (77.70%), 137 (56.30%), 38 (19.60%), 4 (13.30%) and 1 (5.00%) respectively, which were statistically significant with p-value <0.001 .  From all patients, 70% (693) were with any comorbidity and overall survival rate was observed 419 (42.20%). Association of survival rate with vaccination status and waves of disease was found statistically significant with P-value <0.001.

Conclusion: Survival rate was higher in the 3^rd, 4^th, 5^th waves than 1^st, 2nd due to vaccination, whereas morbidity rate was observed high in patients with any comorbidity and patient’s  age >40 years.

Keywords: Retrospective study, case series study, COVID-19, survival rate, isolation