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Incidence and correlates of Barotrauma in COVID-19 Patients; data from a tertiary care hospital of Karachi.

. Fatima Zaina, Qurat ul Ain Khan, Santosh Kumar Sidhwani, Muhammad Fazal Hussain Qureshi, Rameel Muhammad Aftab, Mahira Lakhani, Muhammad Hassan Ayub & Numra Altaf Tunio


Abstract

Barotrauma is one of the major causes of morbidity and mortality amongst covid-19 patients. In our current study, we assessed the incidence of barotrauma in covid-19 patients and its correlation with inflammatory biomarkers and demographic characteristics of patients who were treated in a tertiary care hospital of Karachi. A retrospective cross-sectional study was done using data from patient’s medical records from January 2020 to June 2020.Data about patient’s characteristics and correlation with barotrauma was analyzed and presented in a descriptive way. A total of 469 patients were included in the study out of which 48 patients suffered from barotrauma. Most common type of barotrauma was pneumothorax effecting 73% of the patients followed by pneumomediastinum. Barotrauma was more common in patients who had high levels of inflammatory markers. Comorbid were also compared with timeline of events and type of barotrauma (using chi-square) and p value was significant <0.05; patients having Diabetes, Hypertension, acute and chronic kidney disease. Patients on mechanical ventilation had a higher mortality rate compared to BI-PAP and CPAP. There is a high incidence of barotrauma in covid-19 ARDS patients. Factors affecting the risk of barotrauma amongst these patients include age, co-morbid conditions and inflammatory markers.

Index Terms- barotrauma, BIPAP, CPAP, COVID-19, ventilator

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