Home / Articles
Antimicrobial Resistance of E.coli compared with other Uropathogens in patients with UTI
BACKGROUND: The purpose of the study is to observe antimicrobial resistance of E.coli compared with other uropathogens in patients with UTI. Even though antimicrobial resistance has been increasing over the past years all over the world, and urinary tract infection is also getting common day by day. So it needs a for time to time study to determine antibiotic susceptibility and resistance of E.coli from the cases of UTI, to identify the prevalence of E. coli among other uropathogens in UTI, to find out the most susceptible drugs against different uropathogens causing UTIs.
Methodology: Data was collected according to the rule and regulations set by the ethical committee of university of Lahore. The participants for this data was selected according to the inclusion and exclusion criteria. Three hundred samples was collected from the patients with urinary tract infection symptoms without any age limit and gender discrimination from laboratories. Urine samples was taken in sterile urine culture and sensitivity container. Urine specimens was assessed by dipstick analysis and all specimens with a positive dipstick (at least one positive nitrite reaction or leukocyte reaction) was be process for bacterial culture. Then biochemical tests was applied and results was taken out.
Results: Urine test were performed to check UTIs. Total 500 sample size were tested and most of sample show no-growth, Antibiotic E.coli cause more resistance among all other antibiotics against drugs. Antibiotic E.coli cause more resistance among all other antibiotics against drugs where as other. TGC shows 2 resistance and 50 sensitive to E.coli, The SCF shows 7 resistance and 53 sensitive to E.coli, while other organisms were also involved. The frequency and percentage of both negative is higher whereas nitrate positive is lower among them all.
Conclusion(s): The results obtained in this study indicated that E. coli was the most prevalent uropathogen who cause UTI, being responsible for more than half of the urinary tract infections. The frequency and percentage of both nitrate and leukocyte negative is higher whereas only nitrate positive is lower among them all.
Keywords: Antimicrobial Resistance, E.coli, Uropathogens, UTI.