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Evaluation of Angina Pectoris Treatment : Appropriateness of Indications, Drug Selection and Dosage Accuracy in Tertiary Care Hospital, Peshawar
There are many presentation of coronary artery diseases, out of which angina pectoris is one variety. Angina pectoris is define as chest pain or discomfort due to coronary heart disease, which occurs when the heart muscle doesn’t get sufficient blood as it needs. Angina usually causes uncomfortable pressure, tightness, fullness, squeezing or pain in the center of the chest which radiates to left arm, shoulder and neck, experience a significant rise worldwide, presenting a considerable challenge in contemporary healthcare. This study was an observational study conducted among patients diagnosed with Angina Pectoris based on Canadian Cardiovascular Society Classification of Angina pectoris (CCS), Aiming to assess the appropriateness of drug indications and the selection of prescribed medications for treating Angina pectoris and associated comorbidities, based on relevant clinical guidelines and to evaluate dosage accuracy for effective angina management.
The study examined the baseline characteristics such as gender, age, address and comorbidities of angina patients. All patients included in this study were adults, with a total of 53 participants, comprising 28 males (52.83%) and 25 females (47.17%) of varying ages. Hypertension was the common co-morbidity with (64.14%) in all patients. Diagnosis based on Canadian Cardiovascular Society (CCS) Classification of Angina Pectoris (66%) patients was diagnosed with CCS Ⅱ class. Angiography is an imaging test to view body blood vessels, this test was performed for all patients and found that triple vessel coronary artery disease was among 39.62% patients. Angioplasty is a procedure to widen the narrowed Vessels and was performed for 62.6% Average number of drugs per prescription was 5.62. The most commonly prescribed Anti-anginal drug classes were Beta Blocker, Nitrates, Ranolazine, Trimetazidine, Angiotensin converting enzymes inhibitors, calcium channel blocker, Antiplatelet and Statin. The doses of all the Anti-anginal drug classes were according to the established European society of cardiology (ESC) guideline.
The study concludes that the prescribed medications, which included a variety of Anti-anginal drug classes, were aligned with established European Society of Cardiology (ESC) guidelines, ensuring appropriate drug selection and dosage for effective management of angina and related comorbidities.