Invasion, defined as a forcible entry into a person's domain, provides opportunities for history to be made. It occurs on a massive scale occasionally and has the potential to drastically alter the ecosystem of the nation affected. History, as a record of previous human action, serves as a road map, source of information, and source of criticism. It is unavoidable for any author to describe or depict a nation that is crucial to his or her work. It emphasizes empathy, honesty, understanding, and social conscience through a series of lessons that provide important moral instruction. Literature and history are inextricably linked. Events in history are disordered chronologies of unknown data, necessitating the creation of a paradigm and making sense of them by a historian. In this way, how Amitav Ghosh’s novel The Calcutta Chromosome explores the history of malaria hypotheses is the main discussion of this paper.

KEY WORDS:

            History, reinvent, disease, discovery