The development in aquaculture sector plays major contribution in nations economy. So in fish market the demand for nutrient rich and disease free fishes increasing rapidly. but in another hand  major problem arising due to low nutritional level of supplementary food and in other hand major loss occurred due to Fish diseases and the alternative diet used for fish health improvement are mostly costly to can’t afford by small scale farmers  . The disease outbreak is the sign of lower immune level of fishes due to nutritionally low diet so there is need to develop immunemodulater and best nutritive supplement. so present investigation were focused upon to formulate low coast fish feed with high nutritive value and immune modulator. All the fishes were put in portable plastic pools   each portable plastic pools   stacked with 15 fishes those were fed with Azolla pinnata. Significant results were obtaining in diet containing 350 and 400 g per kilo gram of basal feed. also its shows the greater inhibitory activity against fish pathogens Aeromonas spp.

Index Terms: Cyprinus carpio, , Azolla pinnata ,Aeromonas sp. Fish Feed