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REVIEW ON NARINGIN: METHOD OF ISOLATION, ANALYTICAL DEVELOPMENT AND ITS RECENT PHARMACOLOGICAL ACTIVITIES

. B. Sudarshana, J. Honey, T. Nilotpal and S. Bhupendra


Abstract

Naringin is a flavonoid which can be isolated from different citrus fruits like Grape fruit, Orange, Pomelo, Lemon etc. It can be analysed by using various analytical techniques: HPLC, TLC, UV, HPTLC, mass spectroscopy, Liquid chromatography, Chiral chromatography, LC/mass. Naringin can act as an antioxidant and scavenge free radicals. Naringin mainly focuses on the invitro and invivo animal studies showing   its beneficial effects on cardioprotective, antioxidant anti-inflammatory, antimicrobial, hypolipemiant, neurological, thermogenic, pulmonary disorders and antidiabetic. In this pandemic Naringin is treated as a most promising treatment strategy against Covid-19 due to its antiviral and anti-inflammatory effects. Recently Naringin proven its activity towards various molecular docking studies. Naringin itself keeps the body healthy active against various illness and it is highly active against various major life style disorders and even as an antineoplastic agent.

KEYWORD-

Naringin, Flavonoid, Citrus fruit, Antioxidant.

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